KEGG   Drosophila melanogaster (fruit fly): Dmel_CG6502
Entry
Dmel_CG6502       CDS       T00030                                 
Symbol
E(z)
Name
(RefSeq) enhancer of zeste, isoform B
  KO
K11430  [histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:2.1.1.356]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme00310  Lysine degradation
dme01100  Metabolic pathways
dme03083  Polycomb repressive complex
Brite
KEGG Orthology (KO) [BR:dme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    Dmel_CG6502 (E(z))
 09120 Genetic Information Processing
  09126 Chromosome
   03083 Polycomb repressive complex
    Dmel_CG6502 (E(z))
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dme03036]
    Dmel_CG6502 (E(z))
Enzymes [BR:dme01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.356  [histone H3]-lysine27 N-trimethyltransferase
     Dmel_CG6502 (E(z))
Chromosome and associated proteins [BR:dme03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     Dmel_CG6502 (E(z))
   Polycomb repressive complex (PRC) and associated proteins
    PRC2.1
     Dmel_CG6502 (E(z))
    PRC2.2
     Dmel_CG6502 (E(z))
SSDB
Motif
Pfam: Ezh2_MCSS PRC2_HTH_1 SET preSET_CXC Latrophilin
Other DBs
NCBI-GeneID: 39203
NCBI-ProteinID: NP_001137932
FlyBase: FBgn0000629
UniProt: P42124
Position
3L
AA seq 760 aa
MNSTKVPPEWKRRVKSEYIKIRQQKRYKRADEIKEAWIRNWDEHNHNVQDLYCESKVWQA
KPYDPPHVDCVKRAEVTSYNGIPSGPQKVPICVINAVTPIPTMYTWAPTQQNFMVEDETV
LHNIPYMGDEVLDKDGKFIEELIKNYDGKVHGDKDPSFMDDAIFVELVHALMRSYSKELE
EAAPGTATAIKTETLAKSKQGEDDGVVDVDADGESPMKLEKTDSKGDLTEVEKKETEEPL
ETEDADVKPDVEEVKDKLPFPAPIIFQAISANFPDKGTAQELKEKYIELTEHQDPERPQE
CTPNIDGIKAESVSRERTMHSFHTLFCRRCFKYDCFLHRLQGHAGPNLQKRRYPELKPFA
EPCSNSCYMLIDGMKEKLAADSKTPPIDSCNEASSEDSNDSNSQFSNKDFNHENSKDNGL
TVNSAAVAEINSIMAGMMNITSTQCVWTGADQALYRVLHKVYLKNYCAIAHNMLTKTCRQ
VYEFAQKEDAEFSFEDLRQDFTPPRKKKKKQRLWSLHCRKIQLKKDSSSNHVYNYTPCDH
PGHPCDMNCSCIQTQNFCEKFCNCSSDCQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLC
QACGADQFKLTKITCKNVCVQRGLHKHLLMAPSDIAGWGIFLKEGAQKNEFISEYCGEII
SQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSINPNCYAKVMMVTGDH
RIGIFAKRAIQPGEELFFDYRYGPTEQLKFVGIEREMEIV
NT seq 2283 nt   +upstreamnt  +downstreamnt
atgaatagcactaaagtgccgcccgagtggaagaggcgtgtcaagtcggagtacatcaaa
atcaggcagcagaagcgctacaaacgtgccgacgagatcaaggaggcgtggataagaaac
tgggacgagcacaaccacaatgtacaggatctgtactgcgagtcgaaggtttggcaggct
aaaccctacgatccgccgcatgtggactgtgtgaagcgggcggaggtgactagctacaat
ggcattcccagcggtccgcaaaaggtgcccatttgcgtgatcaacgcggtcactcccata
cccaccatgtacacgtgggcaccaacacagcagaacttcatggtggaggatgagacggtg
ctgcacaatataccctatatgggcgacgaggtcctcgataaggatggcaagttcatagag
gaactgatcaaaaactacgatggcaaggttcacggcgacaaggatccctcgttcatggac
gatgccatcttcgtagaactggtgcacgcccttatgcgctcctacagcaaggaactggag
gaagccgctccgggtacagcgactgccattaaaacagagacgttggcgaaatcaaaacag
ggcgaagatgatggggtagttgatgttgacgcagatggtgaatctcccatgaagcttgag
aaaaccgacagcaaaggggatctgactgaagttgagaagaaggaaactgaagaaccgctg
gagactgaagatgcggatgttaagcccgatgtggaagaagtcaaggacaagctgcccttc
cctgcgcccattatttttcaggccatcagcgctaactttccagacaagggcaccgcgcaa
gagctcaaagaaaagtacattgagcttacggagcaccaggatccggagcgcccacaggag
tgcacacccaacattgacggcatcaaggccgagagcgtttcccgggaaaggactatgcac
tcctttcacacgctcttctgtcgtcgttgcttcaaatacgactgcttcctgcaccgcttg
caaggacatgcgggtcccaatctccagaagcgtcgctatccggaactgaagcctttcgcc
gaaccttgcagcaactcctgctacatgttgatcgatggcatgaaggaaaagctggcggcc
gatagcaagacacctcccattgattcctgcaatgaggccagctccgaggacagtaatgac
agcaacagtcagtttagcaacaaggactttaatcatgagaatagcaaggataatggcctg
actgtaaatagcgccgctgtggctgagatcaactccattatggctggcatgatgaacatc
accagtacgcagtgcgtttggacaggcgctgaccaagcactttatcgggtcttgcataaa
gtgtatttaaagaactactgcgcgattgcgcacaacatgctgaccaagacctgtcgtcag
gtgtacgagtttgcccagaaggaggatgctgagtttagcttcgaggatttgcgacaggac
ttcacacctccgcgcaagaagaagaagaagcaacgtctgtggtcgctgcactgtcgtaag
attcagctaaagaaggactcatcctcgaatcacgtgtacaactacacgccctgcgaccat
cccggacatccatgcgacatgaactgctcctgcattcagacacaaaacttctgcgaaaag
ttctgcaactgcagcagcgattgccagaatcgtttccccggctgtcgctgcaaggctcag
tgcaatacgaagcagtgtccttgctatctggcagtgcgcgagtgtgatcccgatctgtgc
caggcctgcggagcggatcagtttaagctgaccaagatcacgtgcaagaacgtgtgcgtg
cagcgaggactgcacaagcacctgctcatggctccgtctgacatcgccggctggggcatc
tttcttaaggagggtgcgcaaaagaatgagttcatttcggaatattgtggcgagatcata
tcccaagatgaagccgatcgccgtggcaaggtttacgacaagtacatgtgctcatttctt
ttcaatctgaacaacgattttgttgtggatgccactcggaagggcaacaagattcggttt
gccaatcattccattaatcccaattgctatgccaaggttatgatggtcaccggcgatcat
cgcatcggcatctttgccaagcgggccattcagcccggcgaagagctattctttgactac
agatacggacccacggagcagctgaagttcgtgggcatagagcgtgaaatggaaattgtt
tga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (58)   
   KEGG ORTHOLOGY (1)   
   RefGene (53)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (5)   
   Pfam (5)   
All databases (88)   

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